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Zea Mays L.의 불검화 정량추출물(DENTADOL®)이 외과적 치주치료후의 치유에 미치는 효과에 관한 임상적 연구
Clinical trial of unsaponifiable fraction of zea mays L. on healing after surgical periodontal therapy in human

대한치주과학회지 1989년 19권 1호 p.63 ~ 70

최상묵, 한수부, 황광세,

소속 상세정보

최상묵 ( Choi Sang-Mook ) - 서울대학교 치과대학 치주과학교실
한수부 ( Han Soo-Boo ) - 서울대학교 치과대학 치주과학교실
황광세 ( Hwang Kwang-Sei ) - 연세대학교 치과대학 치주과학교실

KMID : 0363019890190010063

Abstract

The efficacy of unsaponifiable fraction of Zea Mays L compared with placebo was evaluated by a double blind method. Subjects were 57 SNUDH out-patients undergoing the Modified Widman flap surgery. The subjects were divided randomly into 2 groups ; 36 subjects were given sugar -coated tablets containing 35mg active drug and 21 were given only placebo sugar-coated tablets. To evaluate the effect, we used a gingival index, pocket depth measurement, a tooth mobility index and the rate of lamina dura appearance. The subjects were evaluated before surgery, 2 weeks, 4 weeks, 8 weeks and 12 weeks after surgery. Zea Mays L seemed to play a significant role in the reduction of gingival inflammation after surgery and was superior to placebo in all parameters and had little adverse effect.